A Fully Spectral 3D Time-Domain Model for Second-Order Simulation of Wavetank Experiments. Part B: Validation; Calibration versus experiments and Sample Applications

International audienceA 3D second-order numerical wavetank (NWT) model, SWEET, is presented. In the first part (A) of the paper [Bonnefoy F, Le Touzé D, Ferrant P. A fully-spectral 3d time-domain model for second-order simultion of wavetank experiments. Part A: Formulation, implementation and numerical properties. Appl Ocean Res 2005. doi:10.1016/j.apor.2006.05.004], the fully-spectral formulation we employ has been detailed, and the numerical properties of the model analyzed. In the present part (B), careful validation by comparison to analytical and experimental results is first reported. Thanks to the efficiency of the proposed spectral method, the shortest wavelengths in the wavetank can be accounted for with moderate computational times. The consequent possibilities are illustrated here for the following 2D and 3D complex wave-pattern simulations, with experimental comparisons: wave-packet and geometric focusing cases, directional wavefields, long-time evolutions of irregular waves. The numerical model features all the physical characteristics of a wavetank (snake wavemaker, experimentally-calibrated absorbing zone, etc.). Its usefulness to help preparing and analyzing experiments is shown in relation to some key practical requirements: e.g. quality and evolution of the usable test zone and usability of enhanced wavemaker motions

3-D HOS simulations of extreme waves in open seas

In the present paper we propose a method for studying extreme-wave appearance based on the Higher-Order Spectral (HOS) technique proposed by West et al. (1987) and Dommermuth and Yue (1987). The enhanced HOS model we use is presented and validated on test cases. Investigations of freak-wave events appearing within long-time evolutions of 2-D and 3-D wavefields in open seas are then realized, and the results are discussed. Such events are obtained in our periodic-domain HOS model by using different kinds of configurations: either i) we impose an initial 3-D directional spectrum with the phases adjusted so as to form a focused <i>forced</i> event after a while, or ii) we let 2-D and 3-D wavefields defined by a directional wave spectrum evolve up to the <i>natural</i> appearance of freak waves. Finally, we investigate the influence of directionality on extreme wave events with an original study of the 3-D shape of the detected freak waves

Theoretical analysis and numerical verification of the consistency of viscous smoothed-particle-hydrodynamics formulations in simulating free-surface flows

The theoretical formulation of the smoothed particle hydrodynamics (SPH) method deserves great care because of some inconsistencies occurring when considering free-surface inviscid flows. Actually, in SPH formulations one usually assumes that (i) surface integral terms on the boundary of the interpolation kernel support are neglected, (ii) free-surface conditions are implicitly verified. These assumptions are studied in detail in the present work for free-surface Newtonian viscous flow. The consistency of classical viscous weakly compressible SPH formulations is investigated. In particular, the principle of virtual work is used to study the verification of the free-surface boundary conditions in a weak sense. The latter can be related to the global energy dissipation induced by the viscous term formulations and their consistency. Numerical verification of this theoretical analysis is provided on three free-surface test cases including a standing wave, with the three viscous term formulations investigated

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.

In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field

EUREC⁴A

The science guiding the EUREC⁴A campaign and its measurements is presented. EUREC⁴A comprised roughly 5 weeks of measurements in the downstream winter trades of the North Atlantic – eastward and southeastward of Barbados. Through its ability to characterize processes operating across a wide range of scales, EUREC⁴A marked a turning point in our ability to observationally study factors influencing clouds in the trades, how they will respond to warming, and their link to other components of the earth system, such as upper-ocean processes or the life cycle of particulate matter. This characterization was made possible by thousands (2500) of sondes distributed to measure circulations on meso- (200 km) and larger (500 km) scales, roughly 400 h of flight time by four heavily instrumented research aircraft; four global-class research vessels; an advanced ground-based cloud observatory; scores of autonomous observing platforms operating in the upper ocean (nearly 10 000 profiles), lower atmosphere (continuous profiling), and along the air–sea interface; a network of water stable isotopologue measurements; targeted tasking of satellite remote sensing; and modeling with a new generation of weather and climate models. In addition to providing an outline of the novel measurements and their composition into a unified and coordinated campaign, the six distinct scientific facets that EUREC⁴A explored – from North Brazil Current rings to turbulence-induced clustering of cloud droplets and its influence on warm-rain formation – are presented along with an overview of EUREC⁴A's outreach activities, environmental impact, and guidelines for scientific practice. Track data for all platforms are standardized and accessible at https://doi.org/10.25326/165 (Stevens, 2021), and a film documenting the campaign is provided as a video supplement

EUREC⁴A

The science guiding the EUREC⁴A campaign and its measurements is presented. EUREC⁴A comprised roughly 5 weeks of measurements in the downstream winter trades of the North Atlantic – eastward and southeastward of Barbados. Through its ability to characterize processes operating across a wide range of scales, EUREC⁴A marked a turning point in our ability to observationally study factors influencing clouds in the trades, how they will respond to warming, and their link to other components of the earth system, such as upper-ocean processes or the life cycle of particulate matter. This characterization was made possible by thousands (2500) of sondes distributed to measure circulations on meso- (200 km) and larger (500 km) scales, roughly 400 h of flight time by four heavily instrumented research aircraft; four global-class research vessels; an advanced ground-based cloud observatory; scores of autonomous observing platforms operating in the upper ocean (nearly 10 000 profiles), lower atmosphere (continuous profiling), and along the air–sea interface; a network of water stable isotopologue measurements; targeted tasking of satellite remote sensing; and modeling with a new generation of weather and climate models. In addition to providing an outline of the novel measurements and their composition into a unified and coordinated campaign, the six distinct scientific facets that EUREC⁴A explored – from North Brazil Current rings to turbulence-induced clustering of cloud droplets and its influence on warm-rain formation – are presented along with an overview of EUREC⁴A's outreach activities, environmental impact, and guidelines for scientific practice. Track data for all platforms are standardized and accessible at https://doi.org/10.25326/165 (Stevens, 2021), and a film documenting the campaign is provided as a video supplement

Using a Non Linear Spectral Model for Preparing Three Dimensional Directional Wave Experiments

International audienc

Generation of Fully-Nonlinear Prescribed Wave Fields using a Higher-Order Spectral Model

International audienc